Mouse Il22ra2 ELISA Kit (V2LY-0626-LY5862)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0092 ng/mL
Detection Range
0.02-6 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
26.6 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Interleukin 22 Receptor Subunit Alpha 2
Function
Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Isoform 1 may play a role in establishing and maintaining successful pregnancy.
Biological Process
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of inflammatory responseIEA:Ensembl
Regulation of tyrosine phosphorylation of STAT proteinISS:UniProtKB
Cellular Location
Secreted

Ke, Y., Li, B. Z., Nguyen, K., Wang, D., Wang, S., Young, C. D., & Wang, X. J. (2023). IL22RA2 is a Smad7 target mediating alleviation of dermatitis and psoriatic phenotypes in mice. Journal of Investigative Dermatology.

Gómez-Fernández, P., Lopez de Lapuente Portilla, A., Astobiza, I., Mena, J., Urtasun, A., Altmann, V., ... & Vandenbroeck, K. (2020). The rare IL22RA2 signal peptide coding variant rs28385692 decreases secretion of IL-22BP isoform-1,-2 and-3 and is associated with risk for multiple sclerosis. Cells, 9(1), 175.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant IL22RA2 protein, His Tag (CAT#: V2LY-0526-LY1568)

Human Recombinant IL22RA2 protein, hFc Tag (CAT#: V2LY-0526-LY4842)

Human Recombinant IL22RA2 protein, hFc Tag-1 (CAT#: V2LY-0526-LY4843)

Human Recombinant IL22RA2 protein, His & hFc Tag (CAT#: V2LY-0526-LY4844)

Human Recombinant IL22RA2 protein, His Tag (CAT#: V2LY-0526-LY4845)

Human Recombinant IL22RA2 protein, His Tag-1 (CAT#: V2LY-0526-LY4846)

Human Recombinant IL22RA2 protein, His Tag-2 (CAT#: V2LY-0526-LY4847)

Human IL22RA2 ELISA Kit (CAT#: V2LY-0626-LY4764)

Related Products

Mouse Anti-IL22RA2 Recombinant Antibody (875504) (CAT#: CBMAB-I1736-YY)

Mouse Anti-IL22RA2 Recombinant Antibody (214518) (CAT#: CBMAB-I0508-YY)

Mouse Anti-IL22RA2 Recombinant Antibody (CBYY-I1045) (CAT#: CBMAB-I2213-YY)

Human Recombinant IL22RA2 protein, His & hFc Tag (CAT#: V2LY-0526-LY4844)

Mouse Anti-IL22RA2 Recombinant Antibody (A538) (CAT#: CBMAB-AP10888LY)

Human Recombinant IL22RA2 protein, hFc Tag (CAT#: V2LY-0526-LY4842)

Mouse Anti-IL22RA2 Recombinant Antibody (CBYY-I1382) (CAT#: CBMAB-I2552-YY)

Human Recombinant IL22RA2 protein, His Tag (CAT#: V2LY-0526-LY4845)

Human Recombinant IL22RA2 protein, hFc Tag-1 (CAT#: V2LY-0526-LY4843)

Human Recombinant IL22RA2 protein, His Tag-1 (CAT#: V2LY-0526-LY4846)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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