Mouse Recombinant PGK1 protein, His Tag (V2LY-0526-LY8773)

Name: Mouse Recombinant PGK1 protein, His Tag
SKU: V2LY-0526-LY8773
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Mouse

Tag

His Tag

Protein Construction

This product is Mouse Recombinant PGK1 protein, His Tag consist of Amino Acid: 1-417 and predicts a molecular mass of 46.00 kDa.

Molecule Mass

46.00 kDa

Sequence

Amino Acid: 1-417

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>95% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Liquid

Buffer

PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

phosphoglycerate kinase 1

Function

Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate (PubMed:30323285, PubMed:7391028).
In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) (PubMed:2324090).
May play a role in sperm motility (PubMed:26677959).

Biological Process

Cellular response to hypoxiaManual Assertion Based On ExperimentIDA:CAFA
Epithelial cell differentiationManual Assertion Based On ExperimentIEP:UniProtKB
GluconeogenesisManual Assertion Based On ExperimentIBA:GO_Central
Glycolytic processManual Assertion Based On ExperimentIMP:CAFA
Negative regulation of angiogenesisManual Assertion Based On ExperimentIMP:CAFA
PhosphorylationISS:UniProtKB
Plasminogen activationManual Assertion Based On ExperimentIMP:CAFA

Cellular Location

Cytoplasm

Involvement in disease

Phosphoglycerate kinase 1 deficiency (PGK1D):
A condition with a highly variable clinical phenotype that includes hemolytic anemia, rhabdomyolysis, myopathy and neurologic involvement. Patients can express one or more of these manifestations.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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