Mouse Tcf7 ELISA Kit (V2LY-0626-LY3252)

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Tested Data
Datasheet
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Basic Information

Sensitivity
0.021 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
45.5 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TCF7 Gene(Protein Coding) Transcription Factor 7
Function
Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages (By similarity).
Required for the development of natural killer receptor-positive lymphoid tissue inducer T-cells (By similarity).
TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes.
Biological Process
Biological Process canonical Wnt signaling pathwayIBA:GO_Central1 Publication
Biological Process cellular response to interleukin-4IDA:UniProtKB1 Publication
Biological Process gamma-delta T cell differentiationISS:UniProtKB
Biological Process immune responseTAS:ProtInc1 Publication
Biological Process regulation of DNA-templated transcriptionISS:UniProtKB
Biological Process regulation of gamma-delta T cell differentiationISS:UniProtKB
Biological Process regulation of transcription by RNA polymerase IIIBA:GO_Central1 Publication
Biological Process T cell receptor V(D)J recombinationIEA:InterPro
Cellular Location
Nucleus
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human TCF7 ELISA Kit (CAT#: V2LY-0626-LY3818)

TCF7 Matched Antibody Pair (1191) (CAT#: APMAB-1191LY)

Antibody Pairs

TCF7 Matched Antibody Pair (1191) (CAT#: APMAB-1191LY)

Related Products

Mouse Anti-TCF7 Recombinant Antibody (1D2) (CAT#: CBMAB-A8962-LY)

Mouse Anti-TCF7 Recombinant Antibody (CBYJT-2273) (CAT#: CBMAB-T1382-YJ)

TCF7 Matched Antibody Pair (1191) (CAT#: APMAB-1191LY)

Human TCF7 ELISA Kit (CAT#: V2LY-0626-LY3818)

Rabbit Anti-TCF7 Recombinant Antibody (CBYJT-2281) (CAT#: CBMAB-T1390-YJ)

Rat Anti-Tcf7 Recombinant Antibody (CBYJT-2283) (CAT#: CBMAB-T1392-YJ)

Mouse Anti-TCF7 Recombinant Antibody (2E9) (CAT#: CBMAB-A8960-LY)

Mouse Anti-TCF7 Recombinant Antibody (CBYJT-2274) (CAT#: CBMAB-T1383-YJ)

Mouse Anti-TCF7 Recombinant Antibody (CBYJT-2277) (CAT#: CBMAB-T1386-YJ)

Mouse Anti-TCF7 Recombinant Antibody (1B3) (CAT#: CBMAB-A8961-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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