Mouse Tnfsf12 ELISA Kit (V2LY-0626-LY3155)

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Tested Data
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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0033 ng/mL
Detection Range
0.006-0.8 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Mouse
Assay Type
Sandwich
Reactivity
Mouse
Assay Time
1.5 h
Molecule Mass
27.4 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
TNFSF12 Gene(Protein Coding) TNF Superfamily Member 12
Function
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Biological Process
Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:ProtInc1 Publication
Biological Process apoptotic signaling pathway Source:UniProtKB
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process endothelial cell migration Source:UniProtKB1 Publication
Biological Process extrinsic apoptotic signaling pathway Source:GO_Central1 Publication
Biological Process immune response Source:InterPro
Biological Process positive regulation of angiogenesis Source:UniProtKB1 Publication
Biological Process positive regulation of endothelial cell proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of protein catabolic process Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Cell membrane
Tumor necrosis factor ligand superfamily member 12, secreted form
Secreted
Isoform TWE-PRIL
Cell membrane
Topology
Cytoplasmic: 1-21
Helical: 22-42
Extracellular: 43-249
PTM
The soluble form derives from the membrane form by proteolytic processing.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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