Mouse Recombinant TNFSF12 protein, hFc Tag (V2LY-0526-LY9038)

Name: Mouse Recombinant TNFSF12 protein, hFc Tag
SKU: V2LY-0526-LY9038
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Mouse

Tag

hFc Tag

Protein Construction

This product is Mouse Recombinant TNFSF12 protein, hFc Tag consist of Amino Acid: 105-249 and predicts a molecular mass of 44.4 kDa.

Molecule Mass

44.4 kDa

Sequence

Amino Acid: 105-249

Species

Mouse

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>85% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

TNFSF12 Gene(Protein Coding) TNF Superfamily Member 12

Function

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.

Biological Process

Biological Process angiogenesis Source:UniProtKB-KW
Biological Process apoptotic process Source:ProtInc1 Publication
Biological Process apoptotic signaling pathway Source:UniProtKB
Biological Process cell differentiation Source:UniProtKB-KW
Biological Process endothelial cell migration Source:UniProtKB1 Publication
Biological Process extrinsic apoptotic signaling pathway Source:GO_Central1 Publication
Biological Process immune response Source:InterPro
Biological Process positive regulation of angiogenesis Source:UniProtKB1 Publication
Biological Process positive regulation of endothelial cell proliferation Source:UniProtKB1 Publication
Biological Process positive regulation of extrinsic apoptotic signaling pathway Source:UniProtKB1 Publication
Biological Process positive regulation of protein catabolic process Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication

Cellular Location

Cell membrane
Tumor necrosis factor ligand superfamily member 12, secreted form
Secreted
Isoform TWE-PRIL
Cell membrane

Topology

Cytoplasmic: 1-21
Helical: 22-42
Extracellular: 43-249

PTM

The soluble form derives from the membrane form by proteolytic processing.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human, Cynomolgus Recombinant TNFSF12 protein, Fc Tag (CAT#: V2LY-0526-LY7702)

Mouse Recombinant TNFSF12 protein, rFc Tag (CAT#: V2LY-0526-LY9039)

Rat Recombinant TNFSF12 protein, hFc Tag (CAT#: V2LY-0526-LY9628)

Related Products

Mouse Anti-TNFSF12 Recombinant Antibody (CBYJT-3923) (CAT#: CBMAB-T3329-YJ)

Mouse Anti-TNFSF12 Recombinant Antibody (CBYJT-3922) (CAT#: CBMAB-T3327-YJ)

Human, Cynomolgus Recombinant TNFSF12 protein, Fc Tag (CAT#: V2LY-0526-LY7702)

Mouse Anti-TNFSF12 Recombinant Antibody (CBYJT-3920) (CAT#: CBMAB-T3325-YJ)

Mouse Recombinant TNFSF12 protein, rFc Tag (CAT#: V2LY-0526-LY9039)

Rat Anti-Tnfsf12 Recombinant Antibody (CBYJT-3926) (CAT#: CBMAB-T3332-YJ)

Rat Recombinant TNFSF12 protein, hFc Tag (CAT#: V2LY-0526-LY9628)

Mouse Anti-TNFSF12 Recombinant Antibody (CBYJT-3921) (CAT#: CBMAB-T3326-YJ)

Mouse Anti-TNFSF12 Recombinant Antibody (CB370) (CAT#: CBMAB-CS370LY)

Rat Anti-Tnfsf12 Recombinant Antibody (MTW-1) (CAT#: CBMAB-T3333-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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