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OSMR Matched Antibody Pair (836) (APMAB-836LY)

This antibody pair set can be used for detecting and quantifying protein level of human OSMR.
See all OSMR antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-OSMR monoclonal antibody, 100 ug
Detection Antibody
Anti-OSMR Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Alternative Names
Oncostatin M Receptor; Interleukin-31 Receptor Subunit Beta; IL-31 Receptor Subunit Beta; IL-31R Subunit Beta; IL-31R-Beta; IL-31RB;
Entrez Gene ID
9180
UniProt ID
Q99650

Polak, K. L., Tamagno, I., Parameswaran, N., Smigiel, J., Chan, E. R., Yuan, X., ... & Jackson, M. W. (2023). Oncostatin-M and OSM-Receptor feed-forward activation of MAPK induces separable stem-like and mesenchymal programs. Molecular Cancer Research, 21(9), 975-990.

Geng, Q., Wang, J., Zhang, W., Zhou, W., Tang, G., & Gu, M. (2023). Oncostatin M receptor is overexpressed in oral squamous cell carcinoma and connected to poor prognosis. Journal of Oral Pathology & Medicine, 52(2), 136-144.

Geethadevi, A., Tsaih, S. W., Nair, A., Ku, Z., Kadamberi, I. P., Parashar, D., ... & Raghavan, P. C. (2023). Oncostatin m receptor signaling reprograms tumor microenvironment for chemoresistance. Cancer Research, 83(7_Supplement), 3653-3653.

Zhou, J., Yang, J., Dong, Y., Shi, Y., Zhu, E., Yuan, H., ... & Wang, B. (2022). Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling. Stem Cell Research & Therapy, 13(1), 278.

Geethadevi, A., Nair, A., Parashar, D., Ku, Z., Xiong, W., Deng, H., ... & Chaluvally-Raghavan, P. (2021). Oncostatin M Receptor–Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. Cancer research, 81(20), 5336-5352.

Houben, E., Hellings, N., & Broux, B. (2019). Oncostatin M, an underestimated player in the central nervous system. Frontiers in immunology, 10, 455653.

Yu, Z., Li, Z., Wang, C., Pan, T., Chang, X., Wang, X., ... & Su, L. (2019). Oncostatin M receptor, positively regulated by SP1, promotes gastric cancer growth and metastasis upon treatment with Oncostatin M. Gastric Cancer, 22, 955-966.

Guo, Q., Guan, G. F., Cao, J. Y., Zou, C. Y., Zhu, C., Cheng, W., ... & Wu, A. H. (2019). Overexpression of oncostatin M receptor regulates local immune response in glioblastoma. Journal of Cellular Physiology, 234(9), 15496-15509.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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