Rat Glp1r ELISA Kit (V2LY-0626-LY1264)

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Tested Data
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0071 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Rat
Assay Type
Sandwich
Reactivity
Rat
Assay Time
1.5 h
Molecule Mass
52.9 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
glucagon like peptide 1 receptor
Function
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449).

Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449).

Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).
Biological Process
Activation of adenylate cyclase activity Source: ProtInc
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: UniProtKB
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
cAMP-mediated signaling Source: UniProtKB
Cell surface receptor signaling pathway Source: InterPro
Positive regulation of blood pressure Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 24-139
Helical: 140-164
Cytoplasmic: 165-175
Helical: 176-201
Extracellular: 202-227
Helical: 228-251
Cytoplasmic: 252-265
Helical: 176-201
Extracellular: 202-227
Helical: 228-251
Cytoplasmic: 252-265
Helical: 266-290
Extracellular: 291-305
Helical: 306-328
Cytoplasmic: 329-348
Helical: 349-370
Extracellular: 371-383
Helical: 384-404
Cytoplasmic: 405-463
PTM
N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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