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RNH1 Matched Antibody Pair (1011) (APMAB-1011LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-RNH1 monoclonal antibody, 100 ug
Detection Antibody
Anti-RNH1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]
Alternative Names
Ribonuclease/Angiogenin Inhibitor 1; Placental Ribonuclease Inhibitor; Placental RNase Inhibitor; RAI; RNH; Ribonuclease/Angiogenin Inhibitor; Testicular Tissue Protein Li 164; Ribonuclease Inhibitor; PRI;
Entrez Gene ID
6050
UniProt ID
P13489
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For research use only. Not intended for any clinical use.

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