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AADAT

AADAT is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the ma

Full Name

Aminoadipate Aminotransferase

Function

Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).

Biological Process

2-oxoglutarate metabolic process
Alpha-amino acid metabolic process
Biosynthetic process
Glutamate metabolic process
Kynurenine metabolic process
L-lysine catabolic process to acetyl-CoA via saccharopine
Lysine catabolic process
Tryptophan catabolic process

Cellular Location

Mitochondrion

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Anti-AADAT antibodies

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Mouse Anti-AADAT Recombinant Antibody (V2-12484) (CBMAB-0974-CN)

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Target: AADAT

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: V2-12484

Application*: WB, IH, IC, IP

Mouse Anti-AADAT Recombinant Antibody (V2-51866) (CBMAB-K0247-LY)

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Target: AADAT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: V2-51866

Application*: WB, IP, IF, E

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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