AADAT
AADAT is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the ma
Full Name
Aminoadipate Aminotransferase
Function
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
Biological Process
2-oxoglutarate metabolic process
Alpha-amino acid metabolic process
Biosynthetic process
Glutamate metabolic process
Kynurenine metabolic process
L-lysine catabolic process to acetyl-CoA via saccharopine
Lysine catabolic process
Tryptophan catabolic process
Alpha-amino acid metabolic process
Biosynthetic process
Glutamate metabolic process
Kynurenine metabolic process
L-lysine catabolic process to acetyl-CoA via saccharopine
Lysine catabolic process
Tryptophan catabolic process
Cellular Location
Mitochondrion
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Anti-AADAT antibodies
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Target: AADAT
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: V2-12484
Application*: WB, IH, IC, IP
Target: AADAT
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: V2-51866
Application*: WB, IP, IF, E
Target: AADAT
Sensitivity: 0.0073 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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