APOC4
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]
Full Name
Apolipoprotein C4
Function
May participate in lipoprotein metabolism.
Biological Process
Intracellular receptor signaling pathway Source: Reactome
Lipid metabolic process Source: ProtInc
Positive regulation of sequestering of triglyceride Source: BHF-UCL
Triglyceride homeostasis Source: BHF-UCL
Very-low-density lipoprotein particle assembly Source: Reactome
Very-low-density lipoprotein particle clearance Source: Reactome
Lipid metabolic process Source: ProtInc
Positive regulation of sequestering of triglyceride Source: BHF-UCL
Triglyceride homeostasis Source: BHF-UCL
Very-low-density lipoprotein particle assembly Source: Reactome
Very-low-density lipoprotein particle clearance Source: Reactome
Cellular Location
Secreted
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Anti-APOC4 antibodies
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Target: APOC4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3D10
Application*: E, IP, WB
Target: APOC4
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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