ATP5F1B

ATP5F1B is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked mul
Full Name
ATP Synthase F1 Subunit Beta
Function
Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F1. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Biological Process
Angiogenesis Source: UniProtKB
ATP biosynthetic process Source: UniProtKB
Cellular response to interleukin-7 Source: Ensembl
Cristae formation Source: Reactome
Generation of precursor metabolites and energy Source: UniProtKB
Lipid metabolic process Source: Ensembl
Mitochondrial ATP synthesis coupled proton transport Source: UniProtKB
Mitochondrion organization Source: Reactome
Negative regulation of cell adhesion involved in substrate-bound cell migration Source: Ensembl
Osteoblast differentiation Source: UniProtKB
Positive regulation of blood vessel endothelial cell migration Source: CAFA
Proton transmembrane transport Source: UniProtKB
Regulation of intracellular pH Source: UniProtKB
Cellular Location
Mitochondrion inner membrane
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Anti-ATP5F1B antibodies

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Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 4.3E8.D10
Application*: WB, IC, IF, IP, FC
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: 7F4
Application*: FC, IC, IF, IH, WB
Target: ATP5F1B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 7E3F2
Application*: WB, IF, IH
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C4
Application*: FC, IC, IF, IH, WB
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Rat
Clone: 6C10
Application*: WB
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6B11
Application*: IH, WB
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Dog, Monkey, Rat
Clone: 4E5
Application*: FC, IC, IF, WB
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H8
Application*: FC, IC, IF, IH, WB
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: E1
Application*: WB, IF, IP, IH, E
Target: ATP5F1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey, Rat
Clone: 1B10
Application*: FC, IC, IF, IH, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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