BMP2K
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
BMP2 inducible kinase
Function
May be involved in osteoblast differentiation.
Biological Process
Positive regulation of Notch signaling pathway Source: GO_Central
Protein phosphorylation Source: GO_Central
Regulation of bone mineralization Source: GO_Central
Regulation of clathrin-dependent endocytosis Source: GO_Central
Protein phosphorylation Source: GO_Central
Regulation of bone mineralization Source: GO_Central
Regulation of clathrin-dependent endocytosis Source: GO_Central
Cellular Location
Nucleus
PTM
Autophosphorylated.
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Anti-BMP2K antibodies
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Target: BMP2K
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-0663
Application*: WB, IP, IF, E
Target: BMP2K
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B19
Application*: WB, E
Target: BMP2K
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F11
Application*: WB, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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