BRD2

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Full Name
bromodomain containing 2
Function
May play a role in spermatogenesis or folliculogenesis (By similarity).
Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.
Biological Process
Neural tube closure Source: Ensembl
Nucleosome assembly Source: UniProtKB
Protein phosphorylation Source: FlyBase
Regulation of transcription by RNA polymerase II Source: UniProtKB
Spermatogenesis Source: ProtInc
Viral process Source: UniProtKB-KW
Cellular Location
Nucleus. Detected on chromatin and nucleosomes.
View more

Anti-BRD2 antibodies

+ Filters
Loading...

Rabbit Anti-BRD2 Recombinant Antibody (D89B4) (CBMAB-CP0020-LY)

Go to compareCompare
Target: BRD2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: D89B4
Application*: WB
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (3D10) (CBMAB-A0876-LY)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3D10
Application*: WB, E
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (CBXF-2735) (CBMAB-F3452-CQ)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Horse, Cattle
Clone: CBXF-2735
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (CBYY-2045) (CBMAB-2394-YY)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-2045
Application*: E, WB, IP
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (CBYY-1864) (CBMAB-2213-YY)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-1864
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (CBYY-0799) (CBMAB-0802-YY)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-0799
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (CBT4681) (V2LY-0625-LY653)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4681
Application*: WB
Datasheet SDS

Mouse Anti-BRD2 Recombinant Antibody (CBT3069) (V2LY-0625-LY652)

Go to compareCompare
Target: BRD2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: CBT3069
Application*: WB, F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry