CCS

CCS (Copper Chaperone For Superoxide Dismutase) is a Protein Coding gene. Diseases associated with CCS include Entropion and Amyotrophic Lateral Sclerosis 1. Among its related pathways are Detoxification of Reactive Oxygen Species and Amyotrophic lateral sclerosis (ALS). Gene Ontology (GO) annotations related to this gene include copper ion binding and copper ion transmembrane transporter activity. An important paralog of this gene is SOD1.
Full Name
Copper Chaperone For Superoxide Dismutase
Function
Delivers copper to copper zinc superoxide dismutase (SOD1).
Biological Process
Cellular response to oxidative stress Source: Reactome
Positive regulation of oxidoreductase activity Source: Ensembl
Protein maturation by copper ion transfer Source: ProtInc
Removal of superoxide radicals Source: GO_Central
Superoxide metabolic process Source: ProtInc
Cellular Location
Cytoplasm
PTM
Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241.
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Anti-CCS antibodies

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Mouse Anti-CCS Recombinant Antibody (CBFYC-1093) (CBMAB-C1150-FY)

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Target: CCS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1093
Application*: E, IF, IP, WB, P
Datasheet SDS

Human CCS ELISA Kit (V2LY-0626-LY4441)

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Target: CCS
Sensitivity: 0.0096 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

CCS Matched Antibody Pair (202) (APMAB-202LY)

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Target: CCS
Specificity: Human
Datasheet SDS

Mouse Anti-CCS Recombinant Antibody (CBXS-2364) (CBMAB-S5122-CQ)

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Target: CCS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Pig
Clone: CBXS-2364
Application*: E, IF, IP, WB, P
Datasheet SDS

Mouse Anti-CCS Recombinant Antibody (CBXC-2039) (CBMAB-C3647-CQ)

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Target: CCS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXC-2039
Application*: E, IF, IP, WB
Datasheet SDS

Mouse Anti-CCS Recombinant Antibody (CBFYC-0232) (CBMAB-C0260-FY)

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Target: CCS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-0232
Application*: E, IF, IP, WB
Datasheet SDS

Mouse Anti-CCS Recombinant Antibody (1E2) (CBMAB-C3923-LY)

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Target: CCS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E2
Application*: E, P, WB, IF, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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