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CD180

CD180 (CD180 Molecule) is a Protein Coding gene. Among its related pathways are Innate Immune System and Activated TLR4 signalling. An important paralog of this gene is TLR4.
Full Name
CD180 Molecule
Function
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Biological Process
B cell proliferation involved in immune response Source: GO_Central
Cellular response to lipopolysaccharide Source: GO_Central
Inflammatory response Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Positive regulation of lipopolysaccharide-mediated signaling pathway Source: MGI
Cellular Location
Cell membrane
Topology
Extracellular: 24-626
Helical: 627-650
Cytoplasmic: 651-661

Anti-CD180 antibodies

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Target: CD180
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C1204
Application*: IP, IF, F
Target: CD180
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: RP/14
Application*: IP, IF, F, E
Target: CD180
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MHR73
Application*: IP, IF, F
Target: CD180
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: G28.8
Application*: F, IP
Target: CD180
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBCNC-011
Application*: E, P
Target: CD180
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 3H1961
Application*: IP, IF, F
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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