CD180
CD180 (CD180 Molecule) is a Protein Coding gene. Among its related pathways are Innate Immune System and Activated TLR4 signalling. An important paralog of this gene is TLR4.
Full Name
CD180 Molecule
Function
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Biological Process
B cell proliferation involved in immune response Source: GO_Central
Cellular response to lipopolysaccharide Source: GO_Central
Inflammatory response Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Positive regulation of lipopolysaccharide-mediated signaling pathway Source: MGI
Cellular response to lipopolysaccharide Source: GO_Central
Inflammatory response Source: UniProtKB-KW
Innate immune response Source: UniProtKB-KW
Positive regulation of lipopolysaccharide-mediated signaling pathway Source: MGI
Cellular Location
Cell membrane
Topology
Extracellular: 24-626
Helical: 627-650
Cytoplasmic: 651-661
Helical: 627-650
Cytoplasmic: 651-661
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Anti-CD180 antibodies
+ Filters

Target: CD180
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3918
Application*: IH, F
Target: CD180
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3081
Application*: IH, IC, F
Target: CD180
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C1204
Application*: IP, IF, F
Target: CD180
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: RP/14
Application*: IP, IF, F, E
Target: CD180
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MHR73
Application*: IP, IF, F
Target: CD180
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: G28.8
Application*: F, IP
Target: CD180
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBCNC-011
Application*: E, P
Target: CD180
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 3H1961
Application*: IP, IF, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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