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CD200R1

CD200R1 (CD200 Receptor 1) is a Protein Coding gene. Diseases associated with CD200R1 include Primary Hypertrophic Osteoarthropathy. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is CD200R1L.
Full Name
CD200 Receptor 1
Function
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Biological Process
Heterotypic cell-cell adhesion Source: ARUK-UCL
Intracellular signal transduction Source: ARUK-UCL
Negative regulation of interleukin-6 production Source: ARUK-UCL
Negative regulation of macrophage migration Source: ARUK-UCL
Negative regulation of neuroinflammatory response Source: ARUK-UCL
Negative regulation of neuron death Source: ARUK-UCL
Negative regulation of T cell migration Source: ARUK-UCL
Regulation of immune response Source: Reactome
Regulation of neuroinflammatory response Source: ARUK-UCL
Signal transduction Source: ARUK-UCL
Viral process Source: UniProtKB-KW
Cellular Location
Isoform 1&4: Cell membrane
Isoform 2&3: Secreted
Topology
Extracellular: 29-243
Helical: 244-264
Cytoplasmic: 265-325
PTM
The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.

Anti-CD200R1 antibodies

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Mouse Anti-CD200R1 Recombinant Antibody (OX-102) (CBMAB-1331-CN)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX-102
Application*: F, C, IP, WB, FN

Rat Anti-CD200R1 Recombinant Antibody (OX-110) (CBMAB-1332-CN)

Datasheet SDS
Target: CD200R1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: OX-110
Application*: F

Rabbit Anti-CD200R1 Recombinant Antibody (CBFYC-0345) (CBMAB-C0384-FY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-0345
Application*: F

Rabbit Anti-CD200R1 Recombinant Antibody (CBFYC-1147) (CBMAB-C1205-FY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-1147
Application*: E

Mouse Anti-CD200R1 Recombinant Antibody (CBFYC-1148) (CBMAB-C1206-FY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Monkey
Clone: CBFYC-1148
Application*: E

Mouse Anti-CD200R1 Recombinant Antibody (CBFYC-1149) (CBMAB-C1207-FY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBFYC-1149
Application*: E, WB

Mouse Anti-CD200R1 Recombinant Antibody (OX108) (CBMAB-C0968-CQ)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: OX108
Application*: F, MC

Mouse Anti-CD200R1 Recombinant Antibody (CBXC-1153) (CBMAB-C1419-CQ)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1153
Application*: F

Rat Anti-CD200R1 Recombinant Antibody (CBXC-1655) (CBMAB-C2941-CQ)

Datasheet SDS
Target: CD200R1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-1655
Application*: F

Mouse Anti-CD200R1 Recombinant Antibody (04) (CBMAB-C0072-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 04
Application*: EC

Mouse Anti-CD200R1 Recombinant Antibody (380525) (CBMAB-C1048-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 380525
Application*: WB, F, MC

Mouse Anti-CD200R1 Recombinant Antibody (380529) (CBMAB-C1049-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 380529
Application*: IC

Mouse Anti-CD200R1 Recombinant Antibody (3H1966) (CBMAB-C1218-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: 3H1966
Application*: F, IH, IP, WB

Mouse Anti-CD200R1 Recombinant Antibody (02) (CBMAB-C1657-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG
Specificity: Monkey
Clone: 02
Application*: ED

Rabbit Anti-CD200R1 Recombinant Antibody (118) (CBMAB-C2470-LY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 118
Application*: E

Rabbit Anti-CD200R1 Recombinant Antibody (19) (CBMAB-C3467-LY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 19
Application*: E

Mouse Anti-CD200R1 Recombinant Antibody (1E3) (CBMAB-C3933-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E3
Application*: E, WB

Rat Anti-CD200R1 Recombinant Antibody (6A385) (CBMAB-C8023-LY)

Datasheet SDS
Target: CD200R1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 6A385
Application*: F

Mouse Anti-CD200R1 Recombinant Antibody (CBYY-C0161) (CBMAB-C0509-YY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBYY-C0161
Application*: F, IH, IP, WB

Mouse Anti-CD200R1 Recombinant Antibody (CBYY-C0203) (CBMAB-C0578-YY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0203
Application*: F

Rat Anti-CD200R1 Recombinant Antibody (CBYY-C1254) (CBMAB-C2691-YY)

Datasheet SDS
Target: CD200R1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C1254
Application*: F

Mouse Anti-CD200R1 Recombinant Antibody (11C4) (CBMAB-C0057-CN)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11C4
Application*: FC

Mouse Anti-CD200R1 Recombinant Antibody (OX102) (CBMAB-C10089-LY)

Datasheet SDS
Target: CD200R1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: OX102
Application*: F

Rat Anti-CD200R1 Recombinant Antibody (OX110) (CBMAB-C10088-LY)

Datasheet SDS
Target: CD200R1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: OX110
Application*: F

Rabbit Anti-CD200R1 Recombinant Antibody (OX108) (CBMAB-AP999LY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: OX108
Application*: FC

Rabbit Anti-CD200R1 Recombinant Antibody (019) (CBMAB-C1645-LY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 019
Application*: E

Rabbit Anti-CD200R1 Recombinant Antibody (181) (CBMAB-C0440-LY)

Datasheet SDS
Target: CD200R1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 181
Application*: F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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