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CISD1

This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
Full Name
CDGSH Iron Sulfur Domain 1
Function
Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity).

May be involved in Fe-S cluster shuttling and/or in redox reactions.
Biological Process
Regulation of cellular respiration Source: Ensembl
Cellular Location
Mitochondrion outer membrane
Topology
Helical: 14-31
Cytoplasmic: 32-108
PTM
Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
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Anti-CISD1 antibodies

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Mouse Anti-CISD1 Recombinant Antibody (3A1) (CBMAB-C5621-LY)

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Target: CISD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 3A1
Application*: WB, IF, IH
Datasheet SDS

Mouse Anti-CISD1 Recombinant Antibody (2B3) (CBMAB-C4687-LY)

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Target: CISD1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 2B3
Application*: WB, IF, F
Datasheet SDS

Mouse Anti-CISD1 Recombinant Antibody (1A8) (CBMAB-C0472-LY)

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Target: CISD1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 1A8
Application*: WB, E, IP, F
Datasheet SDS

Rabbit Anti-CISD1 Recombinant Antibody (CBWJZ-058) (CBMAB-Z0127-WJ)

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Target: CISD1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBWJZ-058
Application*: WB, IP
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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