CXCL16

CXCL16 (C-X-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CXCL16 include Xanthogranulomatous Cholecystitis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity and low-density lipoprotein receptor activity.
Full Name
C-X-C Motif Chemokine Ligand 16
Function
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity).

Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Biological Process
Chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Positive regulation of cell growth Source: BHF-UCL
Positive regulation of cell migration Source: BHF-UCL
Receptor-mediated endocytosis Source: UniProtKB
Response to cytokine Source: BHF-UCL
Response to interferon-gamma Source: BHF-UCL
Response to tumor necrosis factor Source: BHF-UCL
T cell chemotaxis Source: GO_Central
Cellular Location
Cell membrane; Secreted. Also exists as a soluble form.
Topology
Extracellular: 30-205
Helical: 206-226
Cytoplasmic: 227-254
PTM
Glycosylated.
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Anti-CXCL16 antibodies

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Rat Recombinant CXCL16 protein, His Tag (V2LY-0526-LY9318)

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Target: CXCL16
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-198
Tag: His Tag
Datasheet SDS

Mouse Recombinant CXCL16 protein, His Tag-1 (V2LY-0526-LY8178)

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Target: CXCL16
Expressed Host: Yeast
Sequence: Amino Acid: 27-114
Tag: His Tag
Datasheet SDS

Mouse Recombinant CXCL16 protein, His Tag (V2LY-0526-LY8177)

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Target: CXCL16
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-201
Tag: His Tag
Datasheet SDS

Human Recombinant CXCL16 protein, His Tag (V2LY-0526-LY3434)

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Target: CXCL16
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-224
Tag: His Tag
Datasheet SDS

Rat Recombinant CXCL16 protein, hFc Tag (V2LY-0526-LY9317)

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Target: CXCL16
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-198
Tag: hFc Tag
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBT3203) (V2LY-0625-LY1542)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3203
Application*: IH, F
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBT2733) (V2LY-0625-LY1541)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT2733
Application*: F
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBCNC-521) (V2LY-0125-LY687)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Pig
Clone: CBCNC-521
Application*: IF, WB, IH
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBCNC-520) (V2LY-0125-LY686)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNC-520
Application*: IF, WB
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBWJC-3484) (V2LY-0125-LY685)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBWJC-3484
Application*: E, WB
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBXC-2583) (V2LY-0125-LY684)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-2583
Application*: E, WB
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBXC-2775) (V2LY-0125-LY683)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXC-2775
Application*: WB, IP, IF, E
Datasheet SDS

Rat Anti-CXCL16 Recombinant Antibody (CBXC-1048) (V2LY-0125-LY682)

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Target: CXCL16
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBXC-1048
Application*: N, WB, F
Functional Assay
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBXC-2881) (V2LY-0125-LY681)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-2881
Application*: WB, IP, IF, E
Datasheet SDS

Rat Anti-CXCL16 Recombinant Antibody (CBFYC-2511) (V2LY-0125-LY680)

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Target: CXCL16
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-2511
Application*: E, N, WB, IH, F
Functional Assay
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBFYC-2509) (V2LY-0125-LY678)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBFYC-2509
Application*: WB, IF, P
Datasheet SDS

Rat Anti-CXCL16 Recombinant Antibody (CBFYC-2508) (V2LY-0125-LY677)

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Target: CXCL16
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBFYC-2508
Application*: N, WB
Functional Assay
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBFYC-0480) (V2LY-0125-LY676)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYC-0480
Application*: E
Datasheet SDS

Mouse Anti-CXCL16 Recombinant Antibody (CBFYC-2510) (CBMAB-C2584-FY)

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Target: CXCL16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2510
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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