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CXCL16

CXCL16 (C-X-C Motif Chemokine Ligand 16) is a Protein Coding gene. Diseases associated with CXCL16 include Xanthogranulomatous Cholecystitis. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include chemokine activity and low-density lipoprotein receptor activity.

Full Name

C-X-C Motif Chemokine Ligand 16

Function

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity).

Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

Biological Process

Chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Positive regulation of cell growth Source: BHF-UCL
Positive regulation of cell migration Source: BHF-UCL
Receptor-mediated endocytosis Source: UniProtKB
Response to cytokine Source: BHF-UCL
Response to interferon-gamma Source: BHF-UCL
Response to tumor necrosis factor Source: BHF-UCL
T cell chemotaxis Source: GO_Central

Cellular Location

Cell membrane; Secreted. Also exists as a soluble form.

Topology

Extracellular: 30-205
Helical: 206-226
Cytoplasmic: 227-254

PTM

Glycosylated.

Anti-CXCL16 antibodies

Mouse Anti-CXCL16 Recombinant Antibody (CBCNC-521) (CBMAB-C3216-CN)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBCNC-521

Application*: E

Mouse Anti-CXCL16 Recombinant Antibody (CBWJC-3484) (CBMAB-C4714WJ)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBWJC-3484

Application*: WB, IP, IF, E

Mouse Anti-CXCL16 Recombinant Antibody (CBXC-2583) (CBMAB-C5738-CQ)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-2583

Application*: WB

Mouse Anti-CXCL16 Recombinant Antibody (CBXC-2775) (CBMAB-C5737-CQ)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse

Clone: CBXC-2775

Application*: E, WB

Rat Anti-CXCL16 Recombinant Antibody (CBXC-1048) (CBMAB-C1312-CQ)

SDS

Target: CXCL16

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXC-1048

Application*: F

Mouse Anti-CXCL16 Recombinant Antibody (CBXC-2881) (CBMAB-C0212-CQ)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-2881

Application*: WB, IF

Rat Anti-CXCL16 Recombinant Antibody (CBFYC-2511) (CBMAB-C2585-FY)

SDS

Target: CXCL16

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYC-2511

Application*: ED, E, N, WB

Mouse Anti-CXCL16 (AA 49-273) Recombinant Antibody (CBFYC-2510) (CBMAB-C2584-FY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYC-2510

Application*: E, WB

Mouse Anti-CXCL16 Recombinant Antibody (CBFYC-2509) (CBMAB-C2583-FY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Rat

Clone: CBFYC-2509

Application*: E

Rat Anti-CXCL16 Recombinant Antibody (CBFYC-2508) (CBMAB-C2582-FY)

SDS

Target: CXCL16

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBFYC-2508

Application*: N, WB

Rat Anti-CXCL16 Recombinant Antibody (CBFYC-0480) (CBMAB-C0528-FY)

SDS

Target: CXCL16

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYC-0480

Application*: F

Mouse Anti-CXCL16 Recombinant Antibody (02) (CBMAB-C1664-LY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Rat

Clone: 02

Application*: E

Rat Anti-CXCL16 Recombinant Antibody (142417) (CBMAB-C0327-LY)

SDS

Target: CXCL16

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 142417

Application*: WB, N, EC

Mouse Anti-CXCL16 Recombinant Antibody (560) (CBMAB-AP1794LY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse

Clone: 560

Application*: ELISA, WB

Mouse Anti-CXCL16 Recombinant Antibody (CF124) (CBMAB-FT352LY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CF124

Application*: ELISA, WB

Mouse Anti-CXCL16 Recombinant Antibody (CBCNC-520) (CBMAB-C3215-CN)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBCNC-520

Application*: E, WB

Mouse Anti-CXCL16 Recombinant Antibody (GT5212) (CBMAB-C3214-CN)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: GT5212

Application*: WB

Mouse Anti-CXCL16 Recombinant Antibody (2B12) (CBMAB-C4672-LY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2B12

Application*: E, WB

Mouse Anti-CXCL16 Recombinant Antibody (4.4) (CBMAB-C1261-LY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 4.4

Application*: WB, IC/IF

Rat Anti-CXCL16 Recombinant Antibody (256213) (CBMAB-C0743-LY)

SDS

Target: CXCL16

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: 256213

Application*: WB, F, N, MC

Mouse Anti-CXCL16 Recombinant Antibody (22-19-12) (CBMAB-C0668-LY)

SDS

Target: CXCL16

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 22-19-12

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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