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DPT

Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008]

Full Name

Dermatopontin

Function

Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).

Biological Process

Cell adhesion Source: UniProtKB-KW
Collagen fibril organization Source: GO_Central
Negative regulation of cell population proliferation Source: Ensembl

Cellular Location

Extracellular matrix

PTM

Sulfated on tyrosine residue(s).

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Anti-DPT antibodies

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Mouse Anti-DPT Recombinant Antibody (2A11) (CBMAB-D1638-YC)

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Target: DPT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2A11

Application*: E

Mouse Anti-DPT Recombinant Antibody (CBYJT-1200) (V2LY-0425-LY884)

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Target: DPT

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat, Dog, Cattle, Pig

Clone: CBYJT-1200

Application*: WB, IP, IF, E

Mouse Anti-DPT Recombinant Antibody (2A11) (V2LY-0425-LY883)

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Target: DPT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2A11

Application*: E

Mouse Anti-DPT Recombinant Antibody (CBYJT-1200) (CBMAB-T0214-YJ)

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Target: DPT

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-1200

Application*: WB, IC, P, C, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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