DPT

Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008]

Full Name

Dermatopontin

Function

Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).

Biological Process

Cell adhesion Source: UniProtKB-KW
Collagen fibril organization Source: GO_Central
Negative regulation of cell population proliferation Source: Ensembl

Cellular Location

Extracellular matrix

PTM

Sulfated on tyrosine residue(s).

Anti-DPT antibodies

Mouse Anti-DPT Recombinant Antibody (CBYJT-1200) (CBMAB-T0214-YJ)

Datasheet

SDS

Target: DPT

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-1200

Application*: WB, IC, P, C, E

Mouse Anti-DPT Recombinant Antibody (4B1A12) (CBMAB-AP1942LY)

Datasheet

SDS

Target: DPT

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Rat

Clone: 4B1A12

Application*: ELISA, WB

Mouse Anti-DPT Recombinant Antibody (2A11) (CBMAB-D1638-YC)

Datasheet

SDS

Target: DPT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2A11

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)