EID1

EID1 (EP300 Interacting Inhibitor Of Differentiation 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and histone acetyltransferase regulator activity.

Full Name

EP300 Interacting Inhibitor Of Differentiation 1

Research Area

Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.

Biological Process

Cell cycle Source: UniProtKB-KW
Cell differentiation Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: MGI
Regulation of cell differentiation Source: InterPro

Cellular Location

Cytoplasm; Nucleus. May shuttle between nucleus and cytoplasm.

PTM

Ubiquitinated in U2OS osteosarcoma cells and is rapidly degraded by proteasome as cells exit the cell cycle exit.

Anti-EID1 antibodies

Mouse Anti-EID1 Recombinant Antibody (CBFYE-0630) (CBMAB-E1036-FY)

Datasheet

SDS

Target: EID1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Mouse, Rat, Human

Clone: CBFYE-0630

Application*: WB, E, IF

Rabbit Anti-EID1 Recombinant Antibody (EG1057) (CBMAB-EN1247-LY)

Datasheet

SDS

Target: EID1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1057

Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)