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Rabbit Anti-EID1 Recombinant Antibody (EG1057) (CBMAB-EN1247-LY)

The product is antibody recognizes EID1. The antibody EG1057 immunoassay techniques such as: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000.
See all EID1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1057
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human EID1.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
EP300 Interacting Inhibitor Of Differentiation 1
Introduction
EID1 (EP300 Interacting Inhibitor Of Differentiation 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and histone acetyltransferase regulator activity.
Entrez Gene ID
23741
UniProt ID
Q9Y6B2
Alternative Names
EP300 Interacting Inhibitor Of Differentiation 1; CREBBP/EP300 Inhibitory Protein 1; E1A-Like Inhibitor Of Differentiation 1; 21 KDa PRb-Associated Protein; CREBBP/EP300 Inhibitor 1; C15orf3; EID-1; RBP21; CRI1;
Research Area
Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell differentiation Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: MGI
Regulation of cell differentiation Source: InterPro
Cellular Location
Cytoplasm; Nucleus. May shuttle between nucleus and cytoplasm.
PTM
Ubiquitinated in U2OS osteosarcoma cells and is rapidly degraded by proteasome as cells exit the cell cycle exit.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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