FGF21
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016]
Full Name
Fibroblast Growth Factor 21
Research Area
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Biological Process
Animal organ morphogenesis Source: GO_Central
Cell-cell signaling Source: ProtInc
Cell differentiation Source: GO_Central
Cellular response to drug Source: Ensembl
Cellular response to glucagon stimulus Source: Ensembl
Cellular response to glucose stimulus Source: Ensembl
Cellular response to low-density lipoprotein particle stimulus Source: Ensembl
Endoplasmic reticulum unfolded protein response Source: Ensembl
Endothelial cell apoptotic process Source: Ensembl
Fibroblast growth factor receptor signaling pathway Source: GO_Central
Negative regulation of endothelial cell apoptotic process Source: Ensembl
Negative regulation of neuron death Source: Ensembl
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of cold-induced thermogenesis Source: YuBioLab
Positive regulation of ERK1 and ERK2 cascade Source: UniProtKB
Positive regulation of gene expression Source: GO_Central
Positive regulation of glucose import Source: UniProtKB
Positive regulation of low-density lipoprotein receptor activity Source: BHF-UCL
Positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway Source: Ensembl
Positive regulation of protein phosphorylation Source: GO_Central
Positive regulation of triglyceride catabolic process Source: Ensembl
Regulation of cell migration Source: GO_Central
Regulation of low-density lipoprotein particle clearance Source: BHF-UCL
Response to activity Source: Ensembl
Response to methionine Source: Ensembl
Response to nutrient levels Source: Ensembl
Signal transduction Source: ProtInc
Cell-cell signaling Source: ProtInc
Cell differentiation Source: GO_Central
Cellular response to drug Source: Ensembl
Cellular response to glucagon stimulus Source: Ensembl
Cellular response to glucose stimulus Source: Ensembl
Cellular response to low-density lipoprotein particle stimulus Source: Ensembl
Endoplasmic reticulum unfolded protein response Source: Ensembl
Endothelial cell apoptotic process Source: Ensembl
Fibroblast growth factor receptor signaling pathway Source: GO_Central
Negative regulation of endothelial cell apoptotic process Source: Ensembl
Negative regulation of neuron death Source: Ensembl
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of cold-induced thermogenesis Source: YuBioLab
Positive regulation of ERK1 and ERK2 cascade Source: UniProtKB
Positive regulation of gene expression Source: GO_Central
Positive regulation of glucose import Source: UniProtKB
Positive regulation of low-density lipoprotein receptor activity Source: BHF-UCL
Positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway Source: Ensembl
Positive regulation of protein phosphorylation Source: GO_Central
Positive regulation of triglyceride catabolic process Source: Ensembl
Regulation of cell migration Source: GO_Central
Regulation of low-density lipoprotein particle clearance Source: BHF-UCL
Response to activity Source: Ensembl
Response to methionine Source: Ensembl
Response to nutrient levels Source: Ensembl
Signal transduction Source: ProtInc
Cellular Location
Secreted
View more
Anti-FGF21 antibodies
+ Filters
Loading...
CompareTarget: FGF21
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2F11
Application*: WB, E
Target: FGF21
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2975
Application*: E, IP, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: D4
Application*: ICC, IHC, IP, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2980
Application*: E, WB
Target: FGF21
Host: Rat
Antibody Isotype: IgG1, κ
Specificity: Mouse
Clone: CBXF-2976
Application*: E, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2974
Application*: E, IH, IP, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2973
Application*: E, F, IC
Target: FGF21
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXF-1872
Application*: E
Target: FGF21
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-0575
Application*: WB, E
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXF-2615
Application*: WB
Target: FGF21
Host: Goat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2613
Application*: N
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3601
Application*: WB, F
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9E5
Application*: F, P, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-0571
Application*: E, F, IC
Target: FGF21
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3548
Application*: F, P, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2E2
Application*: F, IF, WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBXF-0574
Application*: WB, IC, P, C, E
Target: FGF21
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0573
Application*: WB, IC, P, C, E
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3715
Application*: WB, P, F, IF
Target: FGF21
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1259
Application*: WB, P
Target: FGF21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0572
Application*: WB
Target: FGF21
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2612
Application*: IS
Target: FGF21
Specificity: Human
Target: FGF21
Specificity: Human
Target: FGF21
Specificity: Human
Target: FGF21
Specificity: Human
Target: FGF21
Specificity: Human
Target: FGF21
Specificity: Human
More Infomation
Hot products 
-
Human Anti-SARS-CoV-2 Spike Recombinant Antibody (CBC05) (CBMAB-CR005LY)
-
Rat Anti-ADAM10 Recombinant Antibody (V2-179741) (CBMAB-A1103-YC)
-
Rat Anti-ABCC11 Recombinant Antibody (V2-179001) (CBMAB-A0236-YC)
-
Mouse Anti-AAV-5 Recombinant Antibody (V2-503416) (CBMAB-V208-1402-FY)
-
Mouse Anti-AAV-5 Recombinant Antibody (V2-503417) (CBMAB-V208-1369-FY)
-
Mouse Anti-BHMT Recombinant Antibody (CBYY-0547) (CBMAB-0550-YY)
-
Mouse Anti-CCS Recombinant Antibody (CBFYC-1093) (CBMAB-C1150-FY)
-
Mouse Anti-BLK Recombinant Antibody (CBYY-0618) (CBMAB-0621-YY)
-
Mouse Anti-AKR1C3 Recombinant Antibody (V2-12560) (CBMAB-1050-CN)
-
Mouse Anti-ATG5 Recombinant Antibody (9H197) (CBMAB-A3945-YC)
-
Mouse Anti-ADRB2 Recombinant Antibody (V2-180026) (CBMAB-A1420-YC)
-
Mouse Anti-CCT6A/B Recombinant Antibody (CBXC-0168) (CBMAB-C5570-CQ)
-
Mouse Anti-ABIN2 Recombinant Antibody (V2-179106) (CBMAB-A0349-YC)
-
Mouse Anti-B2M Recombinant Antibody (CBYY-0050) (CBMAB-0050-YY)
-
Mouse Anti-CD59 Recombinant Antibody (CBXC-2097) (CBMAB-C4421-CQ)
-
Mouse Anti-CRTAM Recombinant Antibody (CBFYC-2235) (CBMAB-C2305-FY)
-
Rabbit Anti-CCL5 Recombinant Antibody (R0437) (CBMAB-R0437-CN)
-
Mouse Anti-8-oxoguanine Recombinant Antibody (V2-7697) (CBMAB-1869CQ)
-
Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) (CBMAB-Z0012-WJ)
-
Mouse Anti-AKT1 Recombinant Antibody (V2-180546) (CBMAB-A2070-YC)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry