FRAT1

The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq]
Full Name
frequently rearranged in advanced T-cell lymphomas
Function
Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
Biological Process
Canonical Wnt signaling pathway Source: WormBase
Positive regulation of canonical Wnt signaling pathway Source: WormBase
Cellular Location
Cytoplasm
PTM
Phosphorylated.
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Anti-FRAT1 antibodies

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Mouse Anti-FRAT1 Recombinant Antibody (7C9) (V2LY-1225-LY87)

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Target: FRAT1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7C9
Application*: WB, E
Datasheet SDS

Rabbit Anti-FRAT1 Recombinant Antibody (CBXF-1184) (V2LY-1225-LY85)

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Target: FRAT1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1184
Application*: WB, IF
Datasheet SDS

Mouse Anti-FRAT1 Recombinant Antibody (7C9) (CBMAB-A3168-LY)

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Target: FRAT1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7C9
Application*: WB, E
Datasheet SDS

Rabbit Anti-FRAT1 Recombinant Antibody (CBXF-3193) (CBMAB-F3889-CQ)

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Target: FRAT1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-3193
Application*: E, IF
Datasheet SDS

Rabbit Anti-FRAT1 Recombinant Antibody (CBXF-1184) (CBMAB-F0971-CQ)

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Target: FRAT1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1184
Application*: WB, IP, IC, F
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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