loading...

GLRX

This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Full Name

glutaredoxin (thioltransferase)

Function

Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

Biological Process

Nucleobase-containing small molecule interconversion Source: Reactome
Positive regulation of membrane potential Source: BHF-UCL
Positive regulation of sodium ion transmembrane transporter activity Source: BHF-UCL
Protein deglutathionylation Source: BHF-UCL

Cellular Location

Cytoplasm

View more

Anti-GLRX antibodies

+ Filters

Loading...

Rabbit Anti-GLRX Recombinant Antibody (CBLG1-1302) (CBMAB-G3873-LY)

Compare

Target: GLRX

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBLG1-1302

Application*: E, WB

Mouse Anti-GLRX Recombinant Antibody (CBLG1-1297) (CBMAB-G3868-LY)

Compare

Target: GLRX

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBLG1-1297

Application*: E, IP

Mouse Anti-GLRX Recombinant Antibody (CBLG1-1296) (CBMAB-G3867-LY)

Compare

Target: GLRX

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBLG1-1296

Application*: E, P, WB

Mouse Anti-GLRX Recombinant Antibody (CBLG1-1294) (CBMAB-G3865-LY)

Compare

Target: GLRX

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBLG1-1294

Application*: WB, IP, IF, E, P

Mouse Anti-GLRX Recombinant Antibody (10K210) (CBMAB-G3858-LY)

Compare

Target: GLRX

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 10K210

Application*: E, IP

Mouse Anti-GLRX Recombinant Antibody (CBFYH-0391) (CBMAB-H0596-FY)

Compare

Target: GLRX

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYH-0391

Application*: E, IH, WB

Human Recombinant GRX1 protein, His Tag (V2LY-0526-LY4336)

Compare

Target: GLRX

Expressed Host: E. coli

Sequence: Amino Acid: 1-106

Tag: His Tag

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry