HOXB5
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq]
Full Name
HOXB5
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Biological Process
Anatomical structure morphogenesis Source: ProtInc
Anterior/posterior pattern specification Source: GO_Central
Embryonic skeletal system morphogenesis Source: Ensembl
Endothelial cell differentiation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Anterior/posterior pattern specification Source: GO_Central
Embryonic skeletal system morphogenesis Source: Ensembl
Endothelial cell differentiation Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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Anti-HOXB5 antibodies
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Target: HOXB5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F10
Application*: WB, E
Target: HOXB5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1770
Application*: WB
Target: HOXB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-1768
Application*: DB, WB
Target: HOXB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-1767
Application*: WB
Target: HOXB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-3191
Application*: DB
Target: HOXB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C3
Application*: IP, M
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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