IER2

IER2 (Immediate Early Response 2) is a Protein Coding gene. An important paralog of this gene is IER5.
Full Name
immediate early response 2
Function
DNA-binding protein that seems to act as a transcription factor (PubMed:19584537).

Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity).

May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity).

Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713).
Biological Process
Cell motility Source: UniProtKB
Neuron differentiation Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Response to fibroblast growth factor Source: UniProtKB
Cellular Location
Cytoplasm; Nucleus. Cytoplasmic during quiescence, translocates to the nucleus upon stimulation.
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Anti-IER2 antibodies

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Mouse Anti-IER2 Recombinant Antibody (3E2) (CBMAB-A4234-LY)

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Target: IER2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3E2
Application*: WB, E
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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