IER2

IER2 (Immediate Early Response 2) is a Protein Coding gene. An important paralog of this gene is IER5.

immediate early response 2

DNA-binding protein that seems to act as a transcription factor (PubMed:19584537).

Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity).

May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity).

Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713).

Cell motility Source: UniProtKB
Neuron differentiation Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Response to fibroblast growth factor Source: UniProtKB

Cytoplasm; Nucleus. Cytoplasmic during quiescence, translocates to the nucleus upon stimulation.