KLF15

Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity). Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity). Involved in podocyte differentiation (By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.

Kruppel Like Factor 15

Lysosomal transporter which is essential for liver homeostasis. Required to maintain stability and lysosomal localization of GLMP.

Protein localization to lysosomeISS:UniProtKB
Protein stabilizationISS:UniProtKB

Lysosome membrane

Not N-glycosylated.