KLF3
Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis (By similarity).
Full Name
Kruppel Like Factor 3
Function
Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis (By similarity).
Biological Process
Cellular response to peptideIEA:Ensembl
Multicellular organism developmentManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Multicellular organism developmentManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
PTM
Sumoylated with SUMO1. Sumoylation is enhanced by PIAS1, PIAS2alpha and PIAS2beta, and PIAS4, but not by Pc2. Enhances transcriptional repression, but has no effect on DNA binding. Sumoylation on Lys-198 is the major site (By similarity).
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Anti-KLF3 antibodies
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Target: KLF3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: KLF3B10F1
Application*: DB, WB
Target: KLF3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 8C206
Application*: WB
Target: KLF3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLY1-108
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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