LASP1

This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization. [provided by RefSeq]

Full Name

LIM and SH3 protein 1

Function

Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).

Biological Process

Ion transportISS:UniProtKB

Cellular Location

Cytoplasm, cell cortex
Cytoplasm, cytoskeleton
Associated with the F-actin rich cortical cytoskeleton.

Anti-LASP1 antibodies

Mouse Anti-LASP1 Recombinant Antibody (8C6) (CBMAB-L0706-YJ)

Datasheet

SDS

Target: LASP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Rabbit

Clone: 8C6

Application*: WB, IM

Mouse Anti-LASP1 Recombinant Antibody (CBYJL-1199) (CBMAB-L0707-YJ)

Datasheet

SDS

Target: LASP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1199

Application*: WB, IP, IF, E

Mouse Anti-LASP1 Recombinant Antibody (CBYJL-1201) (CBMAB-L0709-YJ)

Datasheet

SDS

Target: LASP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJL-1201

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)