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LASP1

This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization. [provided by RefSeq]

Full Name

LIM and SH3 protein 1

Function

Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).

Biological Process

Ion transportISS:UniProtKB

Cellular Location

Cytoplasm, cell cortex
Cytoplasm, cytoskeleton
Associated with the F-actin rich cortical cytoskeleton.

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Anti-LASP1 antibodies

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Mouse Anti-LASP1 Recombinant Antibody (8C6) (CBMAB-L0706-YJ)

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Target: LASP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Rabbit

Clone: 8C6

Application*: WB, IM

Mouse Anti-LASP1 Recombinant Antibody (CBYJL-1201) (CBMAB-L0709-YJ)

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Target: LASP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYJL-1201

Application*: E, WB

Mouse Anti-LASP1 Recombinant Antibody (CBYJL-1199) (CBMAB-L0707-YJ)

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Target: LASP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1199

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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