LIPG
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq]
Full Name
LIPG
Function
Exerts both phospholipase and triglyceride lipase activities (PubMed:12032167, PubMed:10318835, PubMed:10192396).
More active as a phospholipase than a triglyceride lipase (PubMed:12032167).
Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates (PubMed:12032167).
Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins (PubMed:12032167, PubMed:10192396).
More active as a phospholipase than a triglyceride lipase (PubMed:12032167).
Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates (PubMed:12032167).
Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins (PubMed:12032167, PubMed:10192396).
Biological Process
Cell population proliferationIEA:Ensembl
Cholesterol homeostasisManual Assertion Based On ExperimentIMP:BHF-UCL
Fatty acid biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
High-density lipoprotein particle remodelingManual Assertion Based On ExperimentIMP:BHF-UCL
Lipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Lipid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Phospholipid catabolic process1 PublicationNAS:BHF-UCL
Phospholipid homeostasisManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of cholesterol transportManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of high-density lipoprotein particle clearanceManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of lipoprotein metabolic processIEA:Ensembl
Response to nutrientIEA:Ensembl
Reverse cholesterol transportManual Assertion Based On ExperimentIMP:BHF-UCL
Triglyceride catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cholesterol homeostasisManual Assertion Based On ExperimentIMP:BHF-UCL
Fatty acid biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
High-density lipoprotein particle remodelingManual Assertion Based On ExperimentIMP:BHF-UCL
Lipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Lipid metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Phospholipid catabolic process1 PublicationNAS:BHF-UCL
Phospholipid homeostasisManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of cholesterol transportManual Assertion Based On ExperimentIDA:BHF-UCL
Positive regulation of high-density lipoprotein particle clearanceManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of lipoprotein metabolic processIEA:Ensembl
Response to nutrientIEA:Ensembl
Reverse cholesterol transportManual Assertion Based On ExperimentIMP:BHF-UCL
Triglyceride catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
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Anti-LIPG antibodies
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CompareTarget: LIPG
Specificity: Human
Target: LIPG
Specificity: Human
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1787
Application*: IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1785
Application*: IF, IH, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 7D1
Application*: IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7C2
Application*: F, IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6B9
Application*: F, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1784
Application*: IF, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1783
Application*: F, IF, IH, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1782
Application*: F, IF, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1781
Application*: E
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4C3
Application*: F, IF
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4C10
Application*: F, IH, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4C1
Application*: F, IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4A9
Application*: E, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4A8
Application*: F, IF, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1780
Application*: F, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C7
Application*: F, IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3C4
Application*: IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2H10
Application*: P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2E7
Application*: F, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1777
Application*: F, IF, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E3
Application*: IF, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E11
Application*: E, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1776
Application*: F, IF, P, IP, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1775
Application*: IF, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYE-1491
Application*: IC, IH
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Pig
Clone: CBFYE-1490
Application*: C, E
Target: LIPG
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBFYE-1489
Application*: C, P
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1487
Application*: IF, IH
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-1486
Application*: F, IF, IH, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYE-1485
Application*: F, IF, IH, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1484
Application*: F, IF, IH, P, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Dog, Goat, Human, Pig, Rabbit
Clone: CBFYE-1483
Application*: C, IF
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYE-1482
Application*: F, IF, C, WB
Target: LIPG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Rat
Clone: CBFYE-1481
Application*: E, F, IH, WB
Target: LIPG
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYE-0215
Application*: C
Target: LIPG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYE-0152
Application*: F, IH, IP, C
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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