MAP3K2

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Full Name
MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2
Function
Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity).
Plays a role in caveolae kiss-and-run dynamics.
Biological Process
Cellular response to mechanical stimulusManual Assertion Based On ExperimentIEP:UniProtKB
Positive regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Protein phosphorylationManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Nucleus
Upon EGF stimulation, translocates into the nucleus.
PTM
Autophosphorylated.
Ubiquitination by XIAP/BIRC4 does not lead to proteasomal degradation.
View more

Anti-MAP3K2 antibodies

+ Filters
Loading...

Mouse Anti-MAP3K2 (AA 42-264) Recombinant Antibody (CBFYM-1522) (CBMAB-M1685-FY)

Go to compareCompare
Target: MAP3K2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBFYM-1522
Application*: WB, IC
Datasheet SDS

Mouse Anti-MAP3K2 Recombinant Antibody (CBFYM-1521) (CBMAB-M1684-FY)

Go to compareCompare
Target: MAP3K2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYM-1521
Application*: IC, IF, WB
Datasheet SDS

Mouse Anti-MAP3K2 Recombinant Antibody (CBFYM-1519) (CBMAB-M1682-FY)

Go to compareCompare
Target: MAP3K2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-1519
Application*: E, WB, IF, IC
Datasheet SDS

Rabbit Anti-MAP3K2 Recombinant Antibody (CBFYM-0296) (CBMAB-M0361-FY)

Go to compareCompare
Target: MAP3K2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0296
Application*: IF
Datasheet SDS

Human Recombinant MAP3K2 protein, STREP-Trx-TEV Tag (V2LY-0526-LY5437)

Go to compareCompare
Target: MAP3K2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: Full length
Tag: STREP-Trx-TEV Tag
Datasheet SDS

Human Recombinant MAP3K2, Active protein, GST Tag (V2LY-0526-LY5436)

Go to compareCompare
Target: MAP3K2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: Full Length
Tag: GST Tag
Datasheet SDS

Mouse Anti-MAP3K2 Recombinant Antibody (CBT874) (V2LY-0625-LY3210)

Go to compareCompare
Target: MAP3K2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT874
Application*: WB, IF, IC, E
Datasheet SDS

Mouse Anti-MAP3K2 Recombinant Antibody (CBT4410) (V2LY-0625-LY2656)

Go to compareCompare
Target: MAP3K2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4410
Application*: IC
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.