ME1

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq]
Full Name
malic enzyme 1, NADP(+)-dependent, cytosolic
Function
Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP+ and divalent metal ions, and decarboxylation of oxaloacetate.
Biological Process
Carbohydrate metabolic process Source: ProtInc
Malate metabolic process Source: UniProtKB
Nucleotide biosynthetic process Source: UniProtKB
Pyruvate metabolic process Source: GO_Central
Regulation of NADP metabolic process Source: CACAO
Response to carbohydrate Source: UniProtKB
Response to hormone Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-ME1 antibodies

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Mouse Anti-ME1 (AA 1-573) Recombinant Antibody (CBFYM-1973) (CBMAB-M2148-FY)

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Target: ME1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-1973
Application*: E, P, WB
Datasheet SDS

Mouse Anti-ME1 Recombinant Antibody (3H5) (CBMAB-A5372-LY)

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Target: ME1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H5
Application*: WB, E
Datasheet SDS

Mouse Anti-ME1 Recombinant Antibody (2A2) (CBMAB-A5370-LY)

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Target: ME1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2A2
Application*: WB, E
Datasheet SDS

Mouse Anti-ME1 Recombinant Antibody (CBFYM-1974) (CBMAB-M2149-FY)

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Target: ME1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYM-1974
Application*: WB, IH, IF, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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