MYL4

Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
Myosin Light Chain 4
Function
Regulatory light chain of myosin. Does not bind calcium.
Biological Process
Cardiac muscle contraction Source: BHF-UCL
Positive regulation of ATP-dependent activity Source: BHF-UCL
Regulation of the force of heart contraction Source: BHF-UCL
Cellular Location
Cytoskeleton
myosin II
Cytosol
Other locations
A band
Involvement in disease
Atrial fibrillation, familial, 18 (ATFB18):
A familial form of atrial fibrillation, a common sustained cardiac rhythm disturbance. Atrial fibrillation is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure.
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Anti-MYL4 antibodies

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Mouse Anti-MYL4 Recombinant Antibody (A1273) (CBMAB-AP4956LY)

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Target: MYL4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: A1273
Application*: Dot blot, ELISA, WB
Datasheet SDS

Mouse Anti-MYL4 Recombinant Antibody (1A11-C8) (CBMAB-A5727-LY)

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Target: MYL4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A11-C8
Application*: WB, E
Datasheet SDS

Mouse Anti-MYL4 (AA 2-197) Recombinant Antibody (CBFYM-2958) (CBMAB-M3153-FY)

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Target: MYL4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-2958
Application*: P, WB
Datasheet SDS

Mouse Anti-MYL4 (AA 1-197) Recombinant Antibody (CBFYM-0141) (CBMAB-M0162-FY)

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Target: MYL4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-0141
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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