NEDD1

Required for mitosis progression. Promotes the nucleation of microtubules from the spindle.
Full Name
neural precursor cell expressed, developmentally down-regulated 1
Function
Required for mitosis progression. Promotes the nucleation of microtubules from the spindle.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Protein localization to centrosome Source: GO_Central
Cellular Location
Centrosome
PTM
During mitosis, prior phosphorylation on Thr-550 by CDK1 promotes subsequent phosphorylation by PLK1 on Thr-382, Ser-397, Ser-426 and Ser-637. Phosphorylated NEDD1 can interact with gamma-tubulin for targeting the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation.
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Anti-NEDD1 antibodies

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Mouse Anti-NEDD1 Recombinant Antibody (H-3) (CBMAB-N1747-WJ)

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Target: NEDD1
Host: Mouse
Specificity: Human
Clone: H-3
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-NEDD1 Recombinant Antibody (7D10) (CBMAB-N1746-WJ)

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Target: NEDD1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse
Clone: 7D10
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-NEDD1 Recombinant Antibody (3H7) (CBMAB-N1745-WJ)

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Target: NEDD1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3H7
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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