NKD1

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003]

Naked Cuticle Homolog 1

Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.

Eye photoreceptor cell differentiationBy SimilarityISS:BHF-UCL
Negative regulation of canonical Wnt signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of convergent extension involved in axis elongationISS:BHF-UCL
Negative regulation of Wnt signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of non-canonical Wnt signaling pathway via JNK cascadeISS:BHF-UCL
Positive regulation of protein catabolic processManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of Wnt signaling pathway, planar cell polarity pathwayISS:BHF-UCL
Regulation of cell migration involved in somitogenic axis elongationBy SimilarityISS:BHF-UCL
Somatic muscle developmentBy SimilarityISS:BHF-UCL
Wnt signaling pathwayIEA:UniProtKB-KW

Cell membrane
Cytoplasm