NKD1

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003]
Full Name
Naked Cuticle Homolog 1
Function
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
Biological Process
Eye photoreceptor cell differentiationBy SimilarityISS:BHF-UCL
Negative regulation of canonical Wnt signaling pathwayManual Assertion Based On ExperimentIMP:BHF-UCL
Negative regulation of convergent extension involved in axis elongationISS:BHF-UCL
Negative regulation of Wnt signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of non-canonical Wnt signaling pathway via JNK cascadeISS:BHF-UCL
Positive regulation of protein catabolic processManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of Wnt signaling pathway, planar cell polarity pathwayISS:BHF-UCL
Regulation of cell migration involved in somitogenic axis elongationBy SimilarityISS:BHF-UCL
Somatic muscle developmentBy SimilarityISS:BHF-UCL
Wnt signaling pathwayIEA:UniProtKB-KW
Cellular Location
Cell membrane
Cytoplasm
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Anti-NKD1 antibodies

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Rabbit Anti-NKD1 Recombinant Antibody (C30F10) (CBMAB-N2527-WJ)

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Target: NKD1
Host: Rabbit
Specificity: Human
Clone: C30F10
Application*: WB, IP
Datasheet SDS

Rabbit Anti-NKD1 Recombinant Antibody (CBWJN-0604) (CBMAB-N2529-WJ)

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Target: NKD1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJN-0604
Application*: IP, WB
Datasheet SDS

Rabbit Anti-NKD1 Recombinant Antibody (CBWJN-1413) (CBMAB-N2528-WJ)

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Target: NKD1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBWJN-1413
Application*: WB, IP, P, IC
Datasheet SDS
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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