NKIRAS1

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Full Name
NFKB inhibitor interacting Ras-like 1
Function
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Biological Process
I-kappaB kinase/NF-kappaB signaling1 PublicationNAS:UniProtKB
Lung alveolus developmentIEA:Ensembl
Ral protein signal transductionIEA:Ensembl
Regulation of tumor necrosis factor-mediated signaling pathwayIEA:Ensembl
Surfactant homeostasisIEA:Ensembl
Cellular Location
Cytoplasm
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Anti-NKIRAS1 antibodies

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Mouse Anti-NKIRAS1 Recombinant Antibody (8L509) (CBMAB-N2538-WJ)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 8L509
Application*: WB
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (8B11) (CBMAB-N2537-WJ)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8B11
Application*: IF, P, WB
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (8A3) (CBMAB-N2536-WJ)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8A3
Application*: WB
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (6C11) (CBMAB-N2535-WJ)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 6C11
Application*: WB, IH, IF
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (2A7) (CBMAB-N2534-WJ)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A7
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (1D2) (CBMAB-N2533-WJ)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D2
Application*: WB, IF
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (CBLY1-170) (CBMAB-K2183-LY)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLY1-170
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (ABM17B5) (CBMAB-K2182-LY)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: ABM17B5
Application*: WB
Datasheet SDS

Mouse Anti-NKIRAS1 Recombinant Antibody (184C278) (CBMAB-K2184-LY)

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Target: NKIRAS1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Cattle, Dog, Horse, Mouse, Pig, Rat, Frog
Clone: 184C278
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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