NRBP1
May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
Full Name
Nuclear Receptor Binding Protein 1
Function
May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
Biological Process
Endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIDA:UniProtKB
Intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, cell cortex
Endomembrane system
Cell projection, lamellipodium
Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
Endomembrane system
Cell projection, lamellipodium
Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
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Anti-NRBP1 antibodies
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Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2C8
Application*: F, IH, P, IP, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Rat, Monkey
Clone: 7C5
Application*: IH, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Monkey
Clone: 6C11
Application*: F, P, IP, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Monkey
Clone: 5C3
Application*: WB, F, IH, IF, IP, P
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F2
Application*: F, IP, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4D2
Application*: E, IF, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4C1
Application*: F, P, IP, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Monkey
Clone: 2H1
Application*: F, IP, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B4
Application*: E, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2A5
Application*: F, P, IP, WB
Target: NRBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Dog, Rat, Monkey
Clone: 7E2
Application*: WB, IH, F, IP
Target: NRBP1
Specificity: Human
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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