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OTX1

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy. [provided by RefSeq]

Full Name

orthodenticle homeobox 1

Function

Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.

Biological Process

Anterior/posterior pattern specificationIEA:Ensembl
Diencephalon morphogenesisIEA:Ensembl
Inner ear morphogenesisIEA:Ensembl
Metencephalon developmentIEA:Ensembl
Midbrain developmentIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Anti-OTX1 antibodies

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Mouse Anti-OTX1 Recombinant Antibody (4E5) (CBMAB-A6263-LY)

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Target: OTX1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4E5

Application*: WB, E

Rabbit Anti-OTX1 Recombinant Antibody (CBXO-0155) (CBMAB-O0733-CQ)

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Target: OTX1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: CBXO-0155

Application*: WB

Mouse Anti-OTX1 Recombinant Antibody (3A5) (CBMAB-O0732-CQ)

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Target: OTX1

Host: Mouse

Specificity: Human

Clone: 3A5

Application*: WB, IP, IF, E

Mouse Anti-OTX1 Recombinant Antibody (1F2) (CBMAB-O0731-CQ)

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Target: OTX1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F2

Application*: E, IF, IR, WB

Mouse Anti-OTX1 (AA 10-116) Recombinant Antibody (3D12) (CBMAB-O0730-CQ)

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Target: OTX1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3D12

Application*: E, IF, WB

Mouse Anti-OTX1 Antibody (Otx-5F5) (CBMAB-0881-YC)

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Target: OTX1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Rat

Clone: Otx-5F5

Application*: WB

Rabbit Anti-OTX1 Recombinant Antibody (BA0236) (CBMAB-0561CQ)

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Target: OTX1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: BA0236

Application*: CI, P, WB

Rabbit Anti-OTX1 Recombinant Antibody (BA0333) (CBMAB-0560CQ)

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Target: OTX1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse, Rat, Human

Clone: BA0333

Application*: WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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