PITPNB

The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. [provided by RefSeq]
Full Name
phosphatidylinositol transfer protein, beta
Function
Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (PubMed:10531358, PubMed:18636990, PubMed:20332109).
Also catalyzes the transfer of sphingomyelin (By similarity).
Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function (PubMed:20332109).
Biological Process
Lipid metabolic process1 PublicationNAS:ProtInc
Nucleus organizationManual Assertion Based On ExperimentTAS:BHF-UCL
Phospholipid transportManual Assertion Based On ExperimentIDA:BHF-UCL
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Golgi apparatus
Golgi apparatus membrane
Endoplasmic reticulum membrane
PTM
Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.
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Anti-PITPNB antibodies

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Mouse Anti-PITPNB Recombinant Antibody (E-2) (CBMAB-P1896-YC)

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Target: PITPNB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: E-2
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-PITPNB Recombinant Antibody (6H10) (CBMAB-P1895-YC)

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Target: PITPNB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6H10
Application*: WB, IH
Datasheet SDS

Mouse Anti-PITPNB Recombinant Antibody (3D3) (CBMAB-P1894-YC)

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Target: PITPNB
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3D3
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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