POU2F1

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.
Full Name
POU class 2 homeobox 1
Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.
(Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Biological Process
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
PTM
Phosphorylated by PRKDC.
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Anti-POU2F1 antibodies

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Mouse Anti-POU2F1 Recombinant Antibody (CB230A) (CBMAB-CA230LY)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB230A
Application*: ELISA, WB
Datasheet SDS

Rabbit Anti-POU2F1 Recombinant Antibody (D7B6) (CBMAB-CP1792-LY)

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Target: POU2F1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D7B6
Application*: WB, IP, CI, CI-seq
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (1E12) (CBMAB-A6894-LY)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1E12
Application*: WB, E
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (YL15) (CBMAB-P2435-YC)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: YL15
Application*: EMSA, IP, WB
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (POU5I097) (CBMAB-1796-YC)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: POU5I097
Application*: WB, F, DB, ICC, IF
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (
29B9) (V2LY-0725-LY61)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 29B9
Application*: E, WB
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (CBT66) (V2LY-0625-LY3828)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT66
Application*: WB, P, IF, IC
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (CB332) (CBMAB-CS332LY)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB332
Application*: WB, IHC
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (CBCNC-685) (CBMAB-C4135-CN)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-685
Application*: WB, P
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (27-7G1) (CBMAB-C4133-CN)

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Target: POU2F1
Host: Mouse
Specificity: Human
Clone: 27-7G1
Application*: WB
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (CBXO-0463) (CBMAB-O0257-CQ)

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Target: POU2F1
Host: Mouse
Specificity: Mouse, Human, Frog
Clone: CBXO-0463
Application*: WB, IP, IF, P
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (CBXO-0336) (CBMAB-O0256-CQ)

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Target: POU2F1
Host: Mouse
Specificity: Human
Clone: CBXO-0336
Application*: WB, IP, IF, E
Datasheet SDS

Rabbit Anti-POU2F1 Recombinant Antibody (CBXO-0424) (CBMAB-O0255-CQ)

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Target: POU2F1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXO-0424
Application*: WB, IP, CI
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (2C5) (CBMAB-O0254-CQ)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2C5
Application*: WB, IP, IF, P, F, E
Datasheet SDS

Mouse Anti-POU2F1 Recombinant Antibody (5G3) (CBMAB-O0253-CQ)

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 5G3
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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