PPP1R9A

PPP1R9A is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM).

Full Name

protein phosphatase 1, regulatory (inhibitor) subunit 9A

Function

Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity (By similarity).

Biological Process

Actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Calcium-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Modulation of chemical synaptic transmissionIEA:Ensembl
Neuron projection developmentManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm, cytoskeleton
Synapse, synaptosome