RABEP2
RABEP2 (Rabaptin, RAB GTPase Binding Effector Protein 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and growth factor activity. An important paralog of this gene is RABEP1.
Full Name
Rabaptin, RAB GTPase Binding Effector Protein 2
Function
Plays a role in membrane trafficking and in homotypic early endosome fusion (PubMed:9524116).
Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100).
By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062).
Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100).
By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062).
Biological Process
Biological Process cell projection organizationIEA:UniProtKB-KW
Biological Process endocytosisIEA:UniProtKB-KW
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulation of cilium assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process endocytosisIEA:UniProtKB-KW
Biological Process protein transportIEA:UniProtKB-KW
Biological Process regulation of cilium assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Early endosome
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, cilium basal body
Early endosome
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Cytoplasm, cytoskeleton, cilium basal body
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Anti-RABEP2 antibodies
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Target: RABEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF356
Application*: ELISA, WB, IHC
Target: RABEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A4A4
Application*: E, WB, IH
Target: RABEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2296
Application*: F
Target: RABEP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2814
Application*: IH, F
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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