RAPGEF6

RAPGEF6 (Rap Guanine Nucleotide Exchange Factor 6) is a Protein Coding gene. Among its related pathways are Ras signaling pathway and Tight junction. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and GTP-dependent protein binding. An important paralog of this gene is ENSG00000273217.
Full Name
Rap guanine nucleotide exchange factor (GEF) 6
Function
Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.
Biological Process
Biological Process microvillus assemblyManual Assertion Based On ExperimentIGI:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein localization to plasma membraneManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of GTPase activity1 PublicationNAS:UniProtKB
Cellular Location
Cytoplasm
Cell membrane
Upon binding to M-Ras, it translocates to the plasma membrane.
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Anti-RAPGEF6 antibodies

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Mouse Anti-RAPGEF6 Recombinant Antibody (F-8) (CBMAB-R1360-CN)

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Target: RAPGEF6
Host: Mouse
Specificity: Human
Clone: F-8
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RAPGEF6 Recombinant Antibody (CBCNR-211) (CBMAB-R1359-CN)

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Target: RAPGEF6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-211
Application*: E, WB, P, IF
Datasheet SDS

Mouse Anti-RAPGEF6 Recombinant Antibody (CBCNR-210) (CBMAB-R1358-CN)

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Target: RAPGEF6
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-210
Application*: E, WB
Datasheet SDS

Mouse Anti-RAPGEF6 Recombinant Antibody (CBCNR-155) (CBMAB-R1357-CN)

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Target: RAPGEF6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-155
Application*: WB, P
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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