RAX

This gene encodes a homeobox-containing transcription factor that functions in eye development. The gene is expressed early in the eye primordia, and is required for retinal cell fate determination and also regulates stem cell proliferation. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma.[provided by RefSeq, Oct 2009]
Full Name
Retina And Anterior Neural Fold Homeobox
Biological Process
Biological Process camera-type eye developmentIEA:Ensembl
Biological Process hypothalamus developmentIEA:Ensembl
Biological Process limb developmentIEA:Ensembl
Biological Process pattern specification processIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process visual perceptionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
Involvement in disease
Microphthalmia, isolated, 3 (MCOP3):
A disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, and other abnormalities may also be present.
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Anti-RAX antibodies

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RAX Matched Antibody Pair (969) (APMAB-969LY)

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Target: RAX
Specificity: Human
Datasheet SDS

Mouse Anti-RAX Monoclonal Antibody (2D12) (CBMAB-0027-LY)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2D12
Application*: IP
Datasheet SDS

RAX Matched Antibody Pair (970) (APMAB-970LY)

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Target: RAX
Specificity: Human
Datasheet SDS

Mouse Anti-RAX Recombinant Antibody (H-7) (CBMAB-R1574-CN)

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Target: RAX
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: H-7
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RAX Recombinant Antibody (G-12) (CBMAB-R1573-CN)

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Target: RAX
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: G-12
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RAX Recombinant Antibody (CBCNR-262) (CBMAB-R1572-CN)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-262
Application*: IF, E, WB
Datasheet SDS

Mouse Anti-RAX Recombinant Antibody (CBCNR-261) (CBMAB-R1571-CN)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-261
Application*: WB
Datasheet SDS

Mouse Anti-RAX Recombinant Antibody (CBCNR-260) (CBMAB-R1570-CN)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-260
Application*: WB
Datasheet SDS

Mouse Anti-RAX Recombinant Antibody (4F4) (CBMAB-R1569-CN)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4F4
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-RAX Monoclonal Antibody (1G11) (CBMAB-0026-LY)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 1G11
Application*: IP, M
Datasheet SDS

Mouse Anti-RAX Monoclonal Antibody (1C8) (CBMAB-0025-LY)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1C8
Application*: IP, M
Datasheet SDS

Mouse Anti-RAX Monoclonal Antibody (1B4) (CBMAB-0024-LY)

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Target: RAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1B4
Application*: IP, M
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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