TAF11

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. [provided by RefSeq]
Full Name
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
Function
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473).
TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473).
The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).
TAF11, together with TAF13 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes (PubMed:33795473).
Biological Process
Biological Process mRNA transcription by RNA polymerase IIIDA:ComplexPortal1 Publication
Biological Process positive regulation by host of viral transcriptionIDA:UniProtKB1 Publication
Biological Process positive regulation of transcription initiation by RNA polymerase IIIDA:ComplexPortal1 Publication
Biological Process protein phosphorylationIDA:ComplexPortal1 Publication
Biological Process RNA polymerase II preinitiation complex assemblyIPI:ComplexPortal1 Publication
Biological Process transcription by RNA polymerase IIIC:UniProtKB1 Publication
Biological Process transcription initiation at RNA polymerase II promoterIC:UniProtKB1 Publication
Cellular Location
Nucleus
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Anti-TAF11 antibodies

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Mouse Anti-TAF11 Recombinant Antibody (3H5) (CBMAB-A8843-LY)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H5
Application*: WB, E
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (3G6) (CBMAB-A8842-LY)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G6
Application*: WB, E
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (3D3) (CBMAB-A8841-LY)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D3
Application*: WB, E
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (2G9) (CBMAB-A8840-LY)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G9
Application*: WB, E
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (3E7) (CBMAB-A8839-LY)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3E7
Application*: WB, E
Datasheet SDS

Recombinant Mouse Anti-TAF11 Recombinant Antibody (2B4) (CBMAB-XB1086-YC)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: 2B4
Application*: E, IF, IP, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1834) (CBMAB-T0898-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1834
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1833) (CBMAB-T0897-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1833
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1832) (CBMAB-T0896-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1832
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1831) (CBMAB-T0895-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1831
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1830) (CBMAB-T0894-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1830
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1829) (CBMAB-T0893-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1829
Application*: E, IF, P, WB
Datasheet SDS

Mouse Anti-TAF11 Recombinant Antibody (CBYJT-1828) (CBMAB-T0892-YJ)

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Target: TAF11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1828
Application*: E, WB, IC, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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