TAF1B
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1B is one of the SL1-specific TAFs.
Full Name
TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit B
Function
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
Biological Process
Biological Process DNA-templated transcriptionNAS:UniProtKB1 Publication
Biological Process nucleolar large rRNA transcription by RNA polymerase IIBA:GO_Central1 Publication
Biological Process RNA polymerase I preinitiation complex assemblyIDA:UniProtKB1 Publication
Biological Process nucleolar large rRNA transcription by RNA polymerase IIBA:GO_Central1 Publication
Biological Process RNA polymerase I preinitiation complex assemblyIDA:UniProtKB1 Publication
Cellular Location
Nucleus, nucleolus
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Anti-TAF1B antibodies
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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1857
Application*: WB
Target: TAF1B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1856
Application*: WB
Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 938C6a
Application*: DB, WB
Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1855
Application*: WB
Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1854
Application*: WB
Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1853
Application*: WB
Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1852
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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