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TAF1B

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1B is one of the SL1-specific TAFs.

Full Name

TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit B

Function

Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.

Biological Process

Biological Process DNA-templated transcriptionNAS:UniProtKB1 Publication
Biological Process nucleolar large rRNA transcription by RNA polymerase IIBA:GO_Central1 Publication
Biological Process RNA polymerase I preinitiation complex assemblyIDA:UniProtKB1 Publication

Cellular Location

Nucleus, nucleolus

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Anti-TAF1B antibodies

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Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1857) (CBMAB-T0925-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1857

Application*: WB

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1856) (CBMAB-T0924-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-1856

Application*: WB

Mouse Anti-TAF1B Recombinant Antibody (938C6a) (CBMAB-T0923-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 938C6a

Application*: DB, WB

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1855) (CBMAB-T0922-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1855

Application*: WB

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1854) (CBMAB-T0921-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1854

Application*: WB

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1853) (CBMAB-T0920-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1853

Application*: WB

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1852) (CBMAB-T0919-YJ)

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Target: TAF1B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-1852

Application*: WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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