TAF1B

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1B is one of the SL1-specific TAFs.
Full Name
TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit B
Function
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
Biological Process
Biological Process DNA-templated transcriptionNAS:UniProtKB1 Publication
Biological Process nucleolar large rRNA transcription by RNA polymerase IIBA:GO_Central1 Publication
Biological Process RNA polymerase I preinitiation complex assemblyIDA:UniProtKB1 Publication
Cellular Location
Nucleus, nucleolus
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Anti-TAF1B antibodies

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Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1857) (CBMAB-T0925-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1857
Application*: WB
Datasheet SDS

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1856) (CBMAB-T0924-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1856
Application*: WB
Datasheet SDS

Mouse Anti-TAF1B Recombinant Antibody (938C6a) (CBMAB-T0923-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 938C6a
Application*: DB, WB
Datasheet SDS

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1855) (CBMAB-T0922-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1855
Application*: WB
Datasheet SDS

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1854) (CBMAB-T0921-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1854
Application*: WB
Datasheet SDS

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1853) (CBMAB-T0920-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1853
Application*: WB
Datasheet SDS

Mouse Anti-TAF1B Recombinant Antibody (CBYJT-1852) (CBMAB-T0919-YJ)

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Target: TAF1B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1852
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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