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TRIM25 Matched Antibody Pair (1276) (APMAB-1276LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-TRIM25 monoclonal antibody, 100 ug
Detection Antibody
Anti-TRIM25 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008]
Alternative Names
Tripartite Motif Containing 25; Zinc Finger Protein 147 (Estrogen-Responsive Finger Protein); Ubiquitin/ISG15-Conjugating Enzyme TRIM25; RING-Type E3 Ubiquitin Transferase TRIM25; Tripartite Motif-Containing Protein 25; RING-Type E3 Ubiquitin Transferase; Estrogen-Responsive Finger Protein; RING Finger Protein 147; ZNF147; RNF147;
Entrez Gene ID
7706
UniProt ID
Q14258
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For research use only. Not intended for any clinical use.

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