Mouse Anti-ALDH1L1 Recombinant Antibody (CBT4009) (V2LY-0625-LY1836)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBT4009
Application
WB, IHC, FC
Immunogen
Purified recombinant fragment of human ALDH1L1 (AA: 10-222) expressed in E. Coli.
Host Species
Mouse
Specificity
Human, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Entrez Gene ID
UniProt ID
Biological Process
10-formyltetrahydrofolate catabolic process Source: ProtInc
Biosynthetic process Source: InterPro
Folic acid metabolic process Source: Reactome
One-carbon metabolic process Source: UniProtKB-KW
Cellular Location
Cytoplasm

Melzer, L., Freiman, T. M., & Derouiche, A. (2021). Rab6A as a pan-astrocytic marker in mouse and human brain, and comparison with other glial markers (GFAP, GS, Aldh1L1, SOX9). Cells, 10(1), 72.

Sharma, J., Krupenko, N. I., Pediaditakis, P., Helke, K., Strickland, K. C., & Krupenko, S. A. (2021). Effect ofALDH1L1folate enzyme on hepatocellular carcinoma inachemical carcinogenesismodel.

Michalovicz, L. T., Kelly, K. A., Vashishtha, S., Ben‐Hamo, R., Efroni, S., Miller, J. V., ... & O’Callaghan, J. P. (2019). Astrocyte‐specific transcriptome analysis using the ALDH1L1 bacTRAP mouse reveals novel biomarkers of astrogliosis in response to neurotoxicity. Journal of neurochemistry, 150(4), 420-440.

Krupenko, S. A., & Krupenko, N. I. (2019). Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression. Chemico-biological interactions, 302, 149-155.

Sukhorukova, E. G., Sufieva, D. A., & Korzhevskii, D. E. (2018). ALDEHYDE DEHYDROGENASE 1L1 IN RAT BRAIN CELLS. Medical academic journal, 18(1), 84-88.

Beniaminov, A. D., Puzanov, G. A., Krasnov, G. S., Kaluzhny, D. N., Kazubskaya, T. P., Braga, E. A., ... & Dmitriev, A. A. (2018). Deep sequencing revealed a cpg methylation pattern associated with aldh1l1 suppression in breast cancer. Frontiers in genetics, 9, 169.

Zhu, G., Liao, X., Han, C., Liu, X., Yu, L., Qin, W., ... & Peng, T. (2017). ALDH1L1 variant rs2276724 and mRNA expression predict post-operative clinical outcomes and are associated with TP53 expression in HBV-related hepatocellular carcinoma. Oncology reports, 38(3), 1451-1463.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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