ALDH1L1
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Full Name
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Biological Process
10-formyltetrahydrofolate catabolic process Source: ProtInc
Biosynthetic process Source: InterPro
Folic acid metabolic process Source: Reactome
One-carbon metabolic process Source: UniProtKB-KW
Biosynthetic process Source: InterPro
Folic acid metabolic process Source: Reactome
One-carbon metabolic process Source: UniProtKB-KW
Cellular Location
Cytoplasm
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Anti-ALDH1L1 antibodies
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Target: ALDH1L1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 19H14L20
Application*: WB, IF, IC
Target: ALDH1L1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: 4A12
Application*: WB, IH, IF
Target: ALDH1L1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse
Clone: 3E9
Application*: E, IF, P, WB
Target: ALDH1L1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBT2134
Application*: WB, IH, F
Target: ALDH1L1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBT4009
Application*: WB, IH, F
Target: ALDH1L1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 7G8
Application*: WB, IF, IC, IH, FC
Target: ALDH1L1
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse
Clone: YY8
Application*: E, IC, IF, IH, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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