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Mouse Anti-ASF1B Recombinant Antibody (1D4) (CBMAB-A3756-YC)

Provided herein is a Mouse monoclonal antibody against Human Anti-Silencing Function 1B Histone Chaperone. The antibody can be used for immunoassay techniques, such as WB, ELISA.
See all ASF1B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D4
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
Recombinant human ASF1B (1-202 aa) purified from E. coli
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 10% Glycerol
Preservative
0.02% sodium azide
Concentration
Recombinant human ASF1B (1-202aa) purified from E. coli.
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Anti-Silencing Function 1B Histone Chaperone
Introduction
ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key r
Entrez Gene ID
55723
UniProt ID
Q9NVP2
Alternative Names
Anti-Silencing Function 1B Histone Chaperone; Anti-Silencing Function Protein 1 Homolog B; CCG1-Interacting Factor A-II; HCIA-II; CIA-II; HAsf1b;
Function
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis.
Biological Process
Blastocyst hatching Source: Ensembl
Cell differentiation Source: UniProtKB-KW
DNA replication-dependent nucleosome assembly Source: UniProtKB
DNA replication-independent nucleosome assembly Source: UniProtKB
Spermatogenesis Source: UniProtKB-KW
Cellular Location
Nucleus
PTM
Phosphorylated by TLK1 and TLK2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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